SCHEMBL1304086

SCHEMBL1304086

[N]=Nc1nc2ccccc2s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 2/20 0.49
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 2/20 0.48
ADRA2A P08913 1/20 0.48
FBP1 P09467 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
DRD2 P14416 1/20 0.48
ALOX15 P16050 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
DRD1 P21728 1/20 0.48
MC5R P33032 1/20 0.48
OPRM1 P35372 1/20 0.48
DRD3 P35462 1/20 0.48
OPRK1 P41145 1/20 0.48
CCR2 P41597 1/20 0.48
HTR6 P50406 1/20 0.48
SLC6A3 Q01959 1/20 0.48
PDK1 Q15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1222858 1.00 INSR (0.49) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL6655466 0.85 HPGD (0.54) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL1506734 0.83 INSR (0.65) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL31314986 0.83 INSR (0.65) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL19849828 0.79 HPGD (0.49) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL10894657 0.79 INSR (0.49) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL10894663 0.79 INSR (0.51) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL6635403 0.79 INSR (0.53) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL1222861 0.79 HPGD (0.53) INSRHPGDHSD17B10ALDH1A1ADRA2A
SCHEMBL6998648 0.79 INSR (0.49) INSRHPGDHSD17B10ALDH1A1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683901-A Benzothiazole heterocyclic azo type water-soluble dye and preparation method thereof 青岛理工大学 2021-11-23 CN claimed
US-7709632-B2 such as porphyrins, chlorins, texaphyrins via cyclization, oligomerization JOHNSON THOMAS E 2010-05-04 US claimed
JP-57096050-A None JP disclosed
JP-59020204-A None JP disclosed
CN-114514277-B Ethylene-alpha-olefin copolymer composition and use thereof 三井化学株式会社 2024-06-18 CN disclosed
US-20220411659-A1 ETHYLENE/alpha-OLEFIN COPOLYMER COMPOSITION AND APPLICATION THEREOF MITSUI CHEMICALS, INC. (JP) 2022-12-29 US disclosed
CN-110408236-B Dispersant, dispersion and ink composition and method for preparing the same 日信化学工业株式会社 2022-10-21 CN disclosed
CN-110872452-B Dispersion composition, dispersion and ink composition, and method for producing same 日信化学工业株式会社 2022-09-20 CN disclosed
CN-111433404-B Printed pile sheet and printing pile sheet 株式会社可乐丽 2022-09-20 CN disclosed
CN-111315798-B Monomer mixture and curable composition containing same 株式会社大赛璐 2022-08-23 CN disclosed
CN-114096710-A Dyed fabric, textile product using dyed fabric, and method for dyeing fabric 帝人株式会社 2022-02-25 CN disclosed
WO-2004024827-A1 PROCESS FOR PREPARING AZO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-03-25 WO disclosed
EP-0188001-B1 OPTICAL INFORMATION RECORDING MEDIUM KURARAY CO., LTD. (JP) 1990-05-02 EP disclosed
US-4686143-A MONOAZOMETAL COMPLEX COMPOUND RECORDING LAYER KURARAY CO., LTD. (JP) 1987-08-11 US disclosed
EP-0188001-A2 Optical information recording medium KURARAY CO., LTD. (JP) 1986-07-23 EP disclosed
JP-S5920204-A CONTROLLING AGENT AGAINST WATER MOLD FOR MARINE RAISING UENO SEIYAKU OYO KENKYUSHO:KK 1984-02-01 JP disclosed
JP-S5796050-A METHOD OF OBTAINING BETA-CRYSTAL FROM BENZOTHIAZOLYLAZO DYE DERIVATIVE SUMITOMO CHEM CO LTD 1982-06-15 JP disclosed
US-4189428-A DYEABILITY, COLORFASTNESS, RESISTANCE TO SUBLIMATION, IMPROVED BRIGHTNESS EASTMAN KODAK COMPANY (US) 1980-02-19 US disclosed
US-4189428-A DYEABILITY, COLORFASTNESS, RESISTANCE TO SUBLIMATION, IMPROVED BRIGHTNESS EASTMAN KODAK COMPANY (US) 1980-02-19 US disclosed
US-3998801-A MONOAZO DYES; POLYAMIDES; RED TO VIOLET SHADES EASTMAN KODAK COMPANY (US) 1976-12-21 US disclosed