Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655466 | 0.85 | HPGD (0.54) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL31314986 | 0.83 | INSR (0.65) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL1506734 | 0.83 | INSR (0.65) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL1222858 | 0.79 | INSR (0.49) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL10894663 | 0.79 | INSR (0.51) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL1222861 | 0.79 | HPGD (0.53) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL1304086 | 0.79 | INSR (0.49) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL19849828 | 0.79 | HPGD (0.49) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL10894657 | 0.79 | INSR (0.49) | INSRMAPTHPGDNPC1RAB9A | |
| SCHEMBL6998648 | 0.79 | INSR (0.49) | INSRMAPTHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435352-A2 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | Wyeth Holdings Corporation (US) | 2004-07-07 | — | — | EP | claimed |
| EP-0582789-B1 | Novel 7-(substituted)-8-(substituted)-9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0582829-B1 | 9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID CO (US) | 2001-09-12 | — | — | EP | claimed |
| EP-0582788-B1 | 7-(Substituted)-9- (substituted glycyl)-amido)-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1998-07-29 | — | — | EP | claimed |
| CN-1033971-C | 9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1997-02-05 | — | — | CN | claimed |
| CN-1033087-C | Novel 7-(substituted)-8-(substituted-9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1996-10-23 | — | — | CN | claimed |
| US-5567692-A | CONTROLLING BACTERIA INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-10-22 | — | — | US | claimed |
| US-5495032-A | AMINATION OF THE CORRESPONDING HALOGEN CONTAINING COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5495031-A | Process for the production of 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5466684-A | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| US-5420272-A | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1995-05-30 | — | — | US | claimed |
| EP-0618190-A1 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-10-05 | — | — | EP | claimed |
| US-5328902-A | Antibiotics | AMERICAN CYANAMID CO. (US) | 1994-07-12 | — | — | US | claimed |
| CN-1087899-A | The 9-[(substituted glycyl) amido)]-6-demethyl-6-deoxidation tsiklomitsin | AMERICAN CYANAMID CO (US) | 1994-06-15 | — | — | CN | claimed |
| CN-1087626-A | The glycyl that novel 7-(replacement)-8-(replacement)-9-[(replaces) amido]-6-demethyl-6-deoxidation tsiklomitsin | AMERICAN CYANAMID CO (US) | 1994-06-08 | — | — | CN | claimed |
| EP-0582788-A1 | 7-(Substituted)-9- (substituted glycyl)-amido)-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0582789-A1 | Novel 7-(substituted)-8-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0582829-A1 | 9-(substituted glycyl) amido - 6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0118685-A1 | Propene derivatives and their use as plant growth inhibitors | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-19 | — | — | EP | claimed |
| EP-0117412-A1 | Propene derivatives and their use as plant growth inhibitors | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-05 | — | — | EP | claimed |