Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536585 | 0.84 | RAPGEF4 (0.43) | POLBMAPTALDH1A1RECQLL3MBTL1 | |
| SCHEMBL10892465 | 0.84 | SMN1; SMN2 (0.55) | POLBMAPTSMN1; SMN2METAP2RAPGEF4 | |
| SCHEMBL10894580 | 0.78 | CHEK1 (0.45) | MAPTALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL10576785 | 0.76 | RAPGEF4 (0.55) | POLBMAPTALDH1A1RECQLL3MBTL1 | |
| SCHEMBL10536567 | 0.76 | CYP2D6 (0.45) | POLBMAPTALDH1A1RECQLL3MBTL1 | |
| SCHEMBL10895441 | 0.76 | SMN1; SMN2 (0.45) | POLBMAPTALDH1A1RECQLL3MBTL1 | |
| SCHEMBL10903069 | 0.75 | RAPGEF4 (0.36) | POLBMAPTALDH1A1RECQLL3MBTL1 | |
| SCHEMBL10899520 | 0.75 | SMN1; SMN2 (0.37) | NQO1POLBMAPTALDH1A1RECQL | |
| SCHEMBL10889054 | 0.74 | METAP2 (0.45) | MAPTALDH1A1LMNAMAPK1METAP2 | |
| SCHEMBL9879136 | 0.74 | CYP19A1 (0.42) | POLBMAPTALDH1A1RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148390-A2 | Basic triphendioxazine dyes, their manufacture and their use | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |