Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866754 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1777232 | 0.74 | NOS2 (0.42) | ALDH1A1TDP1CYP3A4L3MBTL1MAPK1 | |
| SCHEMBL1033135 | 0.74 | BDKRB2 (0.43) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1030656 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL153634 | 0.72 | BDKRB2 (0.48) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL10737305 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL17997753 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1040922 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9478817 | 0.69 | NOS2 (0.39) | ALDH1A1MAPK1HTTKDM4E | |
| SCHEMBL1780256 | 0.69 | NOS2 (0.39) | ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176775-A2 | Halogen-free self-extinguishing thermoplastic moulding composition | BASF Aktiengesellschaft (DE) | 1986-04-09 | — | — | EP | disclosed |