Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoethanamine SCHEMBL10495217 | 0.89 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL14113987 | 0.74 | — | — | |
| Bromide SCHEMBL5839228 | 0.70 | — | — | |
| SCHEMBL1709053 | 0.67 | — | — | |
| SCHEMBL10031061 | 0.66 | — | — | |
| SCHEMBL11144268 | 0.65 | TRPA1 (0.36) | TRPA1ALDH1A1 | |
| SCHEMBL16916992 | 0.63 | TRPA1 (0.46) | TRPA1 | |
| SCHEMBL28646924 | 0.62 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL10770442 | 0.62 | — | — | |
| Sulfuric Acid SCHEMBL2127327 | 0.61 | TP53 (0.41) | TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614712-A | Immunoassays with luciferase labeled ligands or receptors | THE UPJOHN COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0117693-A2 | Enzyme-linked immunoassay, assay kits and pair-binding compounds | THE UPJOHN COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |