⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5839228 | 0.97 | — | — | |
| SCHEMBL10031061 | 0.73 | — | — | |
| SCHEMBL7769008 | 0.73 | — | — | |
| SCHEMBL10770442 | 0.69 | — | — | |
| SCHEMBL5838931 | 0.69 | — | — | |
| Bromide SCHEMBL10896153 | 0.67 | TRPA1 (0.37) | — | |
| SCHEMBL2122982 | 0.65 | — | — | |
| SCHEMBL25205965 | 0.65 | — | — | |
| SCHEMBL14113987 | 0.65 | — | — | |
| SCHEMBL4352167 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349969-A1 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES AG (AT) | 2014-11-27 | — | — | US | disclosed |
| EP-2674161-A1 | FMO3 inhibitors for treating pain | Akron Molecules GmbH (AT) | 2013-12-18 | — | — | EP | disclosed |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | AKRON MOLECULES GMBH (AT) | 2013-09-26 | — | — | US | disclosed |
| US-8247598-B2 | Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof | NEKTAR THERAPEUTICS (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120088927-A1 | Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof | NEKTAR THERAPEUTICS (US) | 2012-04-12 | — | — | US | disclosed |
| US-7598338-B2 | Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof | NEKTAR THERAPEUTICS (US) | 2009-10-06 | — | — | US | disclosed |
| EP-1578843-B1 | METHODS FOR THE FORMATION OF HYDROGELS USING THIOSULFONATE COMPOSITIONS AND USES THEREOF | NEKTAR THERAPEUTICS AL CORP (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20080033105-A1 | Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof | NEKTAR THERAPEUTICS | 2008-02-07 | — | — | US | disclosed |
| US-7312301-B2 | Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1578843-A1 | METHODS FOR THE FORMATION OF HYDROGELS USING THIOSULFONATE COMPOSITIONS AND USES THEREOF | Nektar Therapeutics Al, Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050143484-A1 | Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof | NEKTAR THERAPEUTICS | 2005-06-30 | — | — | US | disclosed |
| WO-2004060967-A1 | METHODS FOR THE FORMATION OF HYDROGELS USING THIOSULFONATE COMPOSITIONS AND USES THEREOF | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |