Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 17/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153425 | 0.89 | ALDH1A1 (0.37) | IMPDH2MEN1ALDH1A1THRBHPGD | |
| SCHEMBL7695445 | 0.85 | IMPDH2 (0.49) | IMPDH2IMPDH1 | |
| SCHEMBL29793435 | 0.85 | IMPDH2 (0.49) | IMPDH2IMPDH1 | |
| SCHEMBL9660607 | 0.83 | IMPDH2 (0.46) | IMPDH2MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL9660599 | 0.83 | IMPDH2 (0.46) | IMPDH2MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL10438625 | 0.82 | IMPDH2 (0.42) | IMPDH2MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL10406356 | 0.81 | IMPDH2 (0.40) | IMPDH2IMPDH1 | |
| SCHEMBL20754226 | 0.80 | CYP4F2 (0.44) | IMPDH2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL1786249 | 0.79 | IMPDH1 (0.50) | IMPDH2IMPDH1 | |
| SCHEMBL10383779 | 0.79 | CA2 (0.35) | IMPDH2MEN1ALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173142-A2 | Process for the preparation of optically active derivatives of hydroquinone | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-03-05 | — | — | EP | disclosed |