Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901142 | 0.86 | HPGD (0.44) | CYP3A4ABCB11CYP1A2TSHRHTR2A | |
| SCHEMBL10897815 | 0.84 | CA12 (0.51) | CYP3A4CYP1A2MAPTALDH1A1POLB | |
| SCHEMBL10897372 | 0.81 | ALDH1A1 (0.54) | CYP3A4ABCB11CYP1A2TSHRHTR2A | |
| SCHEMBL11111665 | 0.79 | ALDH1A1 (0.40) | CYP3A4ABCB11CYP1A2TSHRHTR2A | |
| SCHEMBL13595802 | 0.78 | CYP3A4 (0.58) | CYP3A4CYP1A2MAPTALDH1A1POLB | |
| SCHEMBL11845351 | 0.76 | HNF4A (0.45) | POLBNPSR1CNR2 | |
| SCHEMBL10897157 | 0.75 | PIN1 (0.49) | CYP3A4ABCB11CYP1A2TSHRHTR2A | |
| SCHEMBL11108069 | 0.75 | ALDH1A1 (0.45) | CYP3A4ABCB11CYP1A2TSHRHTR2A | |
| SCHEMBL10896515 | 0.75 | ALDH1A1 (0.41) | CYP3A4CYP1A2HTR2APMP22MAPT | |
| SCHEMBL24436823 | 0.73 | CYP3A4 (0.51) | CYP3A4MAPTALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098012-B1 | PROCESS FOR PREPARING (O-HYDROXYARYL)-METHANOLS | BLASCHIM S.p.A. (IT) | 1986-09-17 | — | — | EP | disclosed |
| EP-0098012-A2 | Process for preparing (o-hydroxyaryl)-methanols | BLASCHIM S.p.A. (IT) | 1984-01-11 | — | — | EP | disclosed |