Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25392921 | 0.83 | MAOA (0.52) | MAOAMAOBMAPKAPK2AHRGAA | |
| SCHEMBL8814941 | 0.81 | MAOA (0.59) | MAOAMAOBMAPKAPK2AHRGAA | |
| SCHEMBL4298022 | 0.79 | MAOA (0.47) | MAOAMAOBMAPKAPK2GAAACSL1 | |
| SCHEMBL10896712 | 0.78 | MAOA (0.46) | MAOAMAOBMAPKAPK2AHRGAA | |
| SCHEMBL29453995 | 0.77 | MAOA (0.64) | MAOAMAOBMAPKAPK2AHRGAA | |
| SCHEMBL10896702 | 0.77 | MAOA (0.44) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| Xanthene SCHEMBL29378346 | 0.73 | MAOA (1.00) | MAOAMAOBMAPKAPK2AHRGAA | |
| Xanthene SCHEMBL30586075 | 0.73 | MAOA (1.00) | MAOAMAOBMAPKAPK2AHRGAA | |
| Xanthene SCHEMBL4267 | 0.73 | MAOA (1.00) | MAOAMAOBMAPKAPK2AHRGAA | |
| Xanthene SCHEMBL9339684 | 0.73 | MAOA (1.00) | MAOAMAOBMAPKAPK2AHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | claimed |
| US-5073176-A | Permselective | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |