SCHEMBL10896771

SCHEMBL10896771

COCC(C)N(C(=O)C(C)Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
THRB P10828 1/20 0.39
HPGD P15428 3/20 0.39
HTT P42858 2/20 0.38
RAB9A P51151 2/20 0.38
TRPM8 Q7Z2W7 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MLYCD O95822 1/20 0.35
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958809 0.87 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2CHRNB2
SCHEMBL10964289 0.85 LMNA (0.41) ALDH1A1LMNATP53SMN1; SMN2CHRNB2
SCHEMBL10582383 0.82 ALDH1A1 (0.67) ALDH1A1LMNATP53SMN1; SMN2CHRNB2
SCHEMBL10371941 0.81 THRB (0.42) ALDH1A1LMNATP53SMN1; SMN2THRB
SCHEMBL2043131 0.80 ALDH1A1 (0.40) ALDH1A1LMNATP53SMN1; SMN2THRB
SCHEMBL10584483 0.79 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2HTT
SCHEMBL11186186 0.77 ALDH1A1 (0.44) ALDH1A1LMNATP53SMN1; SMN2TRPM8
SCHEMBL10896138 0.76 TP53 (0.43) ALDH1A1LMNATP53SMN1; SMN2CHRNB2
SCHEMBL10962754 0.74 ALDH1A1 (0.46) ALDH1A1LMNATP53SMN1; SMN2CHRNB2
SCHEMBL11451628 0.73 POLQ (0.40) ALDH1A1LMNATP53SMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152137-A PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-05-01 US claimed
CN-1517022-A Herbicide-detoxifying agent composition and its use method and use 沈阳化工研究院 2004-08-04 CN disclosed
US-4581060-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-04-08 US disclosed
US-4548756-A PLANT GROWTH REGULATORS, PLANT SAFENING AGENTS CIBA GEIGY CORPORATION (US) 1985-10-22 US disclosed
US-4532732-A PLANT SAFENING AGENTS AND CHLOROACETANILIDE HERBICIDES FOR SERGHUM, RICE AND BARLEY CIBA-GEIGY CORPORATION (US) 1985-08-06 US disclosed
US-4530798-A Containing phenyl or naphthyl ring CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4518536-A Compositions, which promote plant growth and protect plants, based on oxime ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1985-05-21 US disclosed
US-4497745-A Compositions, which promote plant growth and protect plants based on oxide ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1985-02-05 US disclosed
US-4497648-A ANTIDOTES FOR HERBICIDES FOR PLANTS CIBA-GEIGY CORPORATION (US) 1985-02-05 US disclosed
US-4472317-A Compositions which promote plant growth and protect plants, based on oxime ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1984-09-18 US disclosed
US-4466822-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
US-4451286-A PLANT SAFENING CIBA-GEIGY CORPORATION (US) 1984-05-29 US disclosed
US-4415743-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS; ANTIDOTES CIBA-GEIGY CORPORATION (US) 1983-11-15 US disclosed
US-4227917-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as a crop safener CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed
US-4225334-A USED WITH HERBICIDES CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
US-4220464-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as plant growth regulator CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4152137-A PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed