Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897531 | 1.00 | TBXAS1 (0.40) | TBXAS1CYP1A2MEN1KMT2AUSP2 | |
| SCHEMBL10895830 | 0.82 | TDP1 (0.54) | TBXAS1ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10895132 | 0.81 | TDP1 (0.53) | TBXAS1TDP1 | |
| SCHEMBL22013648 | 0.75 | TDP1 (0.58) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL10896638 | 0.72 | TBXAS1 (0.45) | TBXAS1CYP1A2MEN1KMT2AUSP2 | |
| SCHEMBL10896633 | 0.72 | TBXAS1 (0.45) | TBXAS1CYP1A2MEN1KMT2AUSP2 | |
| SCHEMBL29998549 | 0.69 | KDM4E (0.48) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL10897054 | 0.68 | KDM4E (0.41) | TBXAS1CYP1A2MEN1KMT2AUSP2 | |
| SCHEMBL10897048 | 0.68 | KDM4E (0.41) | TBXAS1CYP1A2MEN1KMT2AUSP2 | |
| SCHEMBL29999634 | 0.65 | KDM4E (0.49) | CYP1A2MEN1KMT2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602022-A | VASODILATORS, ANTIAGGREGANT AGENTS, ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1986-07-22 | — | — | US | disclosed |
| US-4510149-A | VASODILATORS, HYPOTENSIVE AGENTS, ANTIARTHRITIC AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-04-09 | — | — | US | disclosed |