Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTR1E | P28566 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627138 | 0.83 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1565214 | 0.80 | SLC6A3 (0.69) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1565823 | 0.79 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4LMNACNR1 | |
| SCHEMBL17847010 | 0.76 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4LMNAMEN1 | |
| SCHEMBL67619 | 0.74 | HTR1E (0.60) | SLC6A3SLC6A2LMNAMEN1HTR1E | |
| SCHEMBL1565904 | 0.74 | MEN1 (0.47) | SLC6A3SLC6A2SLC6A4LMNAMEN1 | |
| SCHEMBL1566296 | 0.74 | EPHX1 (0.43) | SLC6A3LMNAMEN1HTR1EKMT2A | |
| SCHEMBL1565129 | 0.73 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1565613 | 0.72 | OPRM1 (0.48) | SLC6A3LMNAMEN1HTR1EKMT2A | |
| SCHEMBL10895844 | 0.71 | SLC6A3 (0.41) | SLC6A3LMNAMEN1HTR1EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098058-B1 | SYNTHESIS OF PHENYLACETIC ACID ESTERS | ELI LILLY AND COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |