Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.56 |
| ▸ | THRA | P10827 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27878347 | 0.89 | THRA (0.61) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20278348 | 0.87 | MAPT (0.57) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10021819 | 0.83 | L3MBTL1 (0.67) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL508405 | 0.83 | MAPT (0.53) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28199310 | 0.80 | MAPT (0.50) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10031544 | 0.80 | THRA (0.64) | THRBTHRAMAPTKMT2AMEN1 | |
| SCHEMBL9520211 | 0.80 | THRB (0.54) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10452837 | 0.80 | TAAR1 (0.54) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8051337 | 0.80 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL253937 | 0.79 | KMT2A (0.61) | THRBTHRAMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377846-A | Organic compounds | INTRA CELLULAR THERAPIES INC | 2016-03-02 | — | — | CN | disclosed |
| CN-105143229-A | Substituted xanthines and methods of use thereof | HYDRA BIOSCIENCES INC | 2015-12-09 | — | — | CN | disclosed |
| CN-105121423-A | Novel 3- (4- (benzyloxy) phenyl) hex-4-ynoic acid derivative, method for preparing the same, and pharmaceutical composition for preventing and treating metabolic diseases comprising the same as an effective ingredient | HYUNDAI PHARM CO LTD | 2015-12-02 | — | — | CN | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0076996-B1 | CARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1986-01-02 | — | — | EP | disclosed |
| EP-0076996-A1 | Carboxylic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1983-04-20 | — | — | EP | disclosed |