Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890955 | 0.71 | CHRM5 (0.57) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL18966709 | 0.71 | CHRM5 (0.57) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL18329311 | 0.70 | GAA (0.46) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL4655299 | 0.68 | MAPT (0.66) | GAAMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL27313503 | 0.68 | MAPT (0.55) | MAPTALDH1A1TDP1POLBKMT2A | |
| SCHEMBL27843146 | 0.68 | GAA (1.00) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL26628111 | 0.67 | GAA (0.43) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL28102538 | 0.67 | GAA (0.44) | GAACHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL27372120 | 0.66 | MAPT (0.43) | MAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL517623 | 0.64 | MAPT (0.46) | GAAMAPTALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616025-A | ANTIULCER AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-10-07 | — | — | US | disclosed |