Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9826841 | 0.92 | MAPT (0.58) | MAPTTDP1SMN1; SMN2ALDH1A1SLC18A3 | |
| SCHEMBL11277564 | 0.88 | MAPT (0.52) | MAPTTDP1SMN1; SMN2ALDH1A1SLC18A3 | |
| SCHEMBL27749945 | 0.88 | MAPT (0.53) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4153725 | 0.79 | MAPT (0.61) | MAPTTDP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8155209 | 0.79 | MAPT (0.61) | MAPTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2082827 | 0.79 | MAPT (1.00) | MAPTTDP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL10896316 | 0.79 | MAPT (1.00) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11174447 | 0.77 | MAPT (0.50) | MAPTTDP1SMN1; SMN2ALDH1A1HTR2B | |
| SCHEMBL11470095 | 0.77 | MAPT (0.64) | MAPTTDP1SMN1; SMN2ALDH1A1HTR2B | |
| SCHEMBL8923934 | 0.77 | CHRNB2 (0.56) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373834-A | Preparation method of D-biotin intermediate thiazolo hydantoin | 华东理工大学 | 2024-07-23 | — | — | CN | claimed |
| JP-54098759-A | — | — | None | — | — | JP | disclosed |
| EP-4457210-A2 | PROCESS FOR THE PREPARATION OF CYSTEAMINE BITARTRATE AND PRODUCT SO OBTAINED | Recordati Industria Chimica E Farmaceutica SPA (IT) | 2024-11-06 | — | — | EP | disclosed |
| CN-118488942-A | Process for preparing cysteamine bitartrate and products obtained thereby | 瑞蔻达蒂化学和制药工业股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118373834-A | Preparation method of D-biotin intermediate thiazolo hydantoin | 华东理工大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373834-A | Preparation method of D-biotin intermediate thiazolo hydantoin | 华东理工大学 | 2024-07-23 | — | — | CN | disclosed |
| WO-2023126376-A2 | PROCESS FOR THE PREPARATION OF CYSTEAMINE BITARTRATE AND PRODUCT SO OBTAINED | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A. (IT) | 2023-07-06 | — | — | WO | disclosed |
| US-20230202975-A1 | PROCESS FOR THE PREPARATION OF CYSTEAMINE BITARTRATE AND PRODUCT SO OBTAINED | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A. (IT) | 2023-06-29 | — | — | US | disclosed |
| CN-109666006-B | Aryl derivative bithiazole compound and preparation method and application thereof | 烟台大学 | 2022-09-02 | — | — | CN | disclosed |
| EP-3842418-A1 | METHOD FOR THE PURIFICATION OF CYSTEAMINE | Farmabios S.p.A. (IT) | 2021-06-30 | — | — | EP | disclosed |
| EP-0054409-B1 | PREPARATION OF THIAZOLIDINE DERIVATIVES | FINE ORGANICS LIMITED (GB) | 1985-09-18 | — | — | EP | disclosed |
| US-4483706-A | PLANT SAFENING AGENTS | STAUFFER CHEMICAL COMPANY (US) | 1984-11-20 | — | — | US | disclosed |
| US-4400200-A | PLANT SAFENING AGENTS | STAUFFER CHEMICAL COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0054409-A1 | Preparation of thiazolidine derivatives | FINE ORGANICS LIMITED (GB) | 1982-06-23 | — | — | EP | disclosed |
| EP-0002938-B1 | NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4322240-A | Haloacyl and thiohaloacyl aryl-substituted oxazolidines and thiazolidines-herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| US-4289766-A | Heterocyclic carbothioamides | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| JP-S5498759-A | 22*SUBSTITUTED IMINO**NN*33SUBSTITUTED PHENYL**33THIAZOLIDINE CARBOTHIOAMIDES | LILLY CO ELI | 1979-08-03 | — | — | JP | disclosed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| US-4072688-A | Haloacyl and thiohaloacyl aryl-substituted oxazolidines and thiazolidines-herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202975-A1 | PROCESS FOR THE PREPARATION OF CYSTEAMINE BITARTRATE AND PRODUCT SO OBTAINED | PTMA, CBS, TMT1A | MAPT 1408/4885TDP1 4382/4885SMN1; SMN2 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.