Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655299 | 0.74 | MAPT (0.66) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16416924 | 0.73 | MAOA (0.51) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4153725 | 0.71 | MAPT (0.61) | MAPTTDP1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8155209 | 0.71 | MAPT (0.61) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL2082827 | 0.71 | MAPT (1.00) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL27309134 | 0.69 | MAPT (0.55) | MAPTTDP1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL10898596 | 0.68 | GAA (0.51) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2084173 | 0.68 | MAPT (0.62) | MAPTTDP1SMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL9826841 | 0.68 | MAPT (0.58) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4924273 | 0.67 | ALDH1A1 (1.00) | MAPTTDP1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |