Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898561 | 1.00 | ADORA2B (0.39) | ADORA2BPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL10898552 | 1.00 | ADORA2B (0.39) | ADORA2BPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL9622594 | 0.88 | ADORA2B (0.42) | ADORA2BPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL10900730 | 0.88 | ADORA2B (0.42) | ADORA2BPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL9622596 | 0.88 | ADORA2B (0.42) | ADORA2BPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL9671394 | 0.86 | L3MBTL1 (0.42) | ADORA2BPOLBKMT2AL3MBTL1PLA2G7 | |
| SCHEMBL10841698 | 0.86 | L3MBTL1 (0.42) | ADORA2BPOLBKMT2AL3MBTL1PLA2G7 | |
| SCHEMBL9669648 | 0.86 | L3MBTL1 (0.42) | ADORA2BPOLBKMT2AL3MBTL1PLA2G7 | |
| SCHEMBL9668873 | 0.86 | PLA2G7 (0.43) | POLBMEN1KMT2AL3MBTL1PLA2G7 | |
| SCHEMBL10917677 | 0.86 | PLA2G7 (0.43) | POLBMEN1KMT2AL3MBTL1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099091-B1 | HEXAHYDRODIOXOPYRIMIDINES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-29 | — | — | EP | claimed |
| US-4536504-A | ANTITUMOR, ANTIVIRAL, AND ANTIBACTERIAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | claimed |
| EP-0099091-A1 | Hexahydrodioxopyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-01-25 | — | — | EP | claimed |
| EP-0099091-B1 | HEXAHYDRODIOXOPYRIMIDINES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0171942-A1 | Antitumor composition | Takeda Chemical Industries, Ltd. (JP) | 1986-02-19 | — | — | EP | disclosed |
| US-4536504-A | ANTITUMOR, ANTIVIRAL, AND ANTIBACTERIAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0099091-A1 | Hexahydrodioxopyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-01-25 | — | — | EP | disclosed |