Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900394 | 0.88 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL7520065 | 0.88 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4419522 | 0.87 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL1763346 | 0.87 | POLG (0.42) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL585723 | 0.86 | POLG (0.60) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6914072 | 0.83 | POLG (0.62) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL17215882 | 0.83 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4461899 | 0.83 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL1274297 | 0.83 | POLG (0.72) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL8560606 | 0.80 | TYMS (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005684-A1 | N4-METHYL-2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE AND ITS USE IN POLYMERASE-CATALYZED NUCLEIC ACID SYNTHESES | LIFE TECHNOLOGIES, INC. (US) | 1994-03-17 | — | — | WO | claimed |
| WO-1994005684-A1 | N4-METHYL-2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE AND ITS USE IN POLYMERASE-CATALYZED NUCLEIC ACID SYNTHESES | LIFE TECHNOLOGIES, INC. (US) | 1994-03-17 | — | — | WO | disclosed |