Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899595 | 0.87 | KCNH2 (0.57) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL5857488 | 0.84 | KCNH2 (0.57) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| Acetic Acid SCHEMBL27373593 | 0.81 | SIGMAR1 (0.66) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL2302994 | 0.81 | ITGB3 (0.61) | SIGMAR1FFAR1KEAP1ITGB3ITGA2B | |
| SCHEMBL5857485 | 0.81 | KCNH2 (0.57) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL314574 | 0.80 | SIGMAR1 (0.52) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL10898434 | 0.80 | CYP4F2 (0.56) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL14478358 | 0.80 | SIGMAR1 (0.52) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL3634794 | 0.80 | KCNH2 (0.59) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL3963041 | 0.79 | SIGMAR1 (0.79) | KCNH2KCNJ1SIGMAR1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0076996-A1 | Carboxylic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1983-04-20 | — | — | EP | disclosed |