Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900760 | 0.94 | CACNA1C (0.70) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7431826 | 0.90 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10481007 | 0.88 | CACNA1C (0.64) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10743484 | 0.88 | CACNA1C (0.64) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11781966 | 0.88 | CACNA1C (0.67) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9765702 | 0.85 | CACNA1C (0.66) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11869125 | 0.85 | CACNA1C (0.66) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10902136 | 0.85 | LMNA (0.54) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11814102 | 0.84 | CACNA1C (0.67) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10749230 | 0.84 | CACNA1F (0.59) | CACNA1CCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | claimed |
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |