Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900514 | 0.87 | ALDH1A1 (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL14351291 | 0.79 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL21378211 | 0.79 | — | — | |
| SCHEMBL10766755 | 0.79 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL524128 | 0.76 | ALDH1A1 (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL3446474 | 0.75 | THRB (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL10703811 | 0.75 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL4340349 | 0.72 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL10430813 | 0.72 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL584057 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184924-A2 | Lens composition, articles and method of manufacture | PARAGON OPTICAL INC (US) | 1986-06-18 | — | — | EP | disclosed |