SCHEMBL4340349

SCHEMBL4340349

C=C(C)C(=O)O[SiH](CCC)O[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3998703 0.87 TSHR (0.33) TSHRTHRB
SCHEMBL9240926 0.87 TSHR (0.34) TSHRALDH1A1THRB
SCHEMBL1273423 0.86 ALDH1A1 (0.35) TSHRALDH1A1THRB
SCHEMBL4059702 0.83 ALDH1A1 (0.35) TSHRALDH1A1THRB
SCHEMBL524128 0.80 ALDH1A1 (0.41) TSHRALDH1A1THRB
SCHEMBL3446474 0.79 THRB (0.39) TSHRALDH1A1THRB
SCHEMBL10703811 0.79 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL919874 0.76 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL919921 0.76 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL396695 0.74 THRB (0.46) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104335075-B Method for making fully polymerized UV blocking silicone hydrogel lenses 博士伦公司 2018-03-30 CN claimed
CN-104335075-A Method for making fully polymerized UV blocking silicone hydrogel lenses BAUSCH & LOMB 2015-02-04 CN claimed
US-20040235997-A1 Thermal coating materials and coating materials that can be cured thermally and using actinic radiation and the use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-11-25 US claimed
EP-1423481-A1 THERMAL COATING MATERIALS AND COATING MATERIALS THAT CAN BE CURED THERMALLY AND USING ACTINIC RADIATION AND THE USE THEREOF BASF Coatings AG (DE) 2004-06-02 EP claimed
WO-2003016411-A1 THERMAL COATING MATERIALS AND COATING MATERIALS THAT CAN BE CURED THERMALLY AND USING ACTINIC RADIATION AND THE USE THEREOF BASF COATINGS AG (DE) 2003-02-27 WO claimed
CN-104335075-B Method for making fully polymerized UV blocking silicone hydrogel lenses 博士伦公司 2018-03-30 CN disclosed
CN-105209936-A Optical element for correcting color blindness NITTO DENKO CORP 2015-12-30 CN disclosed
CN-104898187-A Ophthalmic devices comprising photochromic materials with reactive substituents JOHNSON & JOHNSON VISION CARE 2015-09-09 CN disclosed
CN-101208621-B Ophthalmic devices comprising photochromic materials having reactive substituents JOHNSON & JOHNSON VISION CARE 2015-05-20 CN disclosed
CN-104335075-A Method for making fully polymerized UV blocking silicone hydrogel lenses BAUSCH & LOMB 2015-02-04 CN disclosed
EP-2138546-B1 Method for producing wear-resistant, scratch-resistant surfaces FLOORING TECHNOLOGIES LTD (MT) 2013-05-29 EP disclosed
EP-2138546-A2 Method for producing wear-resistant, scratch-resistant surfaces and accessory for a varnish or an artificial resin Flooring Technologies Ltd. (MT) 2009-12-30 EP disclosed
EP-1862227-A2 Array ultrasonic probe and ultrasonic diagnostic apparatus Kabushiki Kaisha Toshiba (JP) 2007-12-05 EP disclosed
WO-2006024360-A1 COATING COMPOUNDS CONTAINING POLYMER PARTICLES CONTAINING ACTIVE COMPOUNDS WITH A PARTICULAR CAPACITY FOR ADHERING TO SUBSTRATES BASF AKTIENGESELLSCHAFT (DE) 2006-03-09 WO disclosed
CN-1168723-A Silicone-containing polymers suitable for ophthalmic applications CIBA GEIGY AG (CH) 1997-12-24 CN disclosed