Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulfurous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL10901320 | 0.86 | MEN1 (0.57) | CYP3A4LMNACYP1A2MAOAGAA | |
| Sulfurous Acid SCHEMBL27998330 | 0.83 | MAPT (0.53) | CYP3A4LMNAMAPTMEN1KMT2A | |
| Alcohol SCHEMBL27933948 | 0.83 | MEN1 (0.53) | CYP3A4LMNACYP1A2MAOAGAA | |
| Sulfurous Acid SCHEMBL11071488 | 0.79 | ACHE (0.68) | CYP3A4LMNACYP1A2MAOAMAPT | |
| Sulfuric Acid SCHEMBL27914272 | 0.79 | TSHR (0.54) | CYP3A4LMNACYP1A2MAOAGAA | |
| Sulfurous Acid SCHEMBL11076739 | 0.79 | ACHE (0.68) | CYP3A4LMNACYP1A2MAOAMAPT | |
| Benzidine SCHEMBL27812588 | 0.78 | CYP3A4 (0.65) | CYP3A4LMNACYP1A2MAOAGAA | |
| Sulfurous Acid SCHEMBL2495585 | 0.76 | — | — | |
| Alcohol SCHEMBL11649562 | 0.76 | MEN1 (0.44) | CYP3A4LMNACYP1A2MAOAGAA | |
| 4-Aminophenol SCHEMBL28648672 | 0.76 | ALDH1A1 (0.72) | CYP3A4LMNACYP1A2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344463-A | OXIDATION | CLAIROL, INC. (US) | 1994-09-06 | — | — | US | disclosed |