Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367448 | 0.84 | OPRM1 (0.49) | KMT2AMEN1OPRM1CHRM4DRD2 | |
| SCHEMBL1307812 | 0.81 | OPRM1 (0.55) | OPRM1CHRM4DRD2BCHEACHE | |
| SCHEMBL7549641 | 0.80 | KCNA3 (0.59) | KMT2AL3MBTL1KCNA3MEN1MCHR1 | |
| SCHEMBL10901335 | 0.78 | OPRM1 (0.40) | CCR5OPRM1CHRM4DRD2BCHE | |
| SCHEMBL10367449 | 0.78 | OPRM1 (0.47) | KMT2AMEN1OPRM1CHRM4DRD2 | |
| SCHEMBL2241424 | 0.78 | KMT2A (0.63) | KMT2AL3MBTL1KCNA3MEN1MCHR1 | |
| SCHEMBL178929 | 0.78 | KMT2A (0.63) | KMT2AL3MBTL1KCNA3MEN1MCHR1 | |
| SCHEMBL2241423 | 0.78 | KMT2A (0.63) | KMT2AL3MBTL1KCNA3MEN1MCHR1 | |
| SCHEMBL31397617 | 0.76 | KMT2A (0.56) | KMT2AL3MBTL1KCNA3MEN1MCHR1 | |
| SCHEMBL555251 | 0.76 | KMT2A (0.62) | KMT2AL3MBTL1KCNA3MEN1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604401-A | QUINOLINE-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |