Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MBTPS1 | Q14703 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367449 | 0.86 | OPRM1 (0.47) | OPRM1SIGMAR1MBTPS1KCNH2CHRM2 | |
| SCHEMBL10367448 | 0.83 | OPRM1 (0.49) | OPRM1SIGMAR1KCNH2CHRM2CHRM3 | |
| SCHEMBL10901330 | 0.78 | KMT2A (0.47) | OPRM1CHRM4DRD2BCHECCR5 | |
| SCHEMBL3815654 | 0.76 | SIGMAR1 (0.51) | OPRM1SIGMAR1KCNH2CHRM4DRD2 | |
| SCHEMBL7507555 | 0.76 | SIGMAR1 (0.51) | OPRM1SIGMAR1KCNH2CHRM4DRD2 | |
| SCHEMBL1307812 | 0.75 | OPRM1 (0.55) | OPRM1SIGMAR1KCNH2CHRM2CHRM3 | |
| SCHEMBL34474746 | 0.75 | CCR5 (0.53) | OPRM1SIGMAR1CHRM2CHRM3CHRM4 | |
| SCHEMBL7499304 | 0.75 | CCR5 (0.53) | OPRM1SIGMAR1CHRM2CHRM3CHRM4 | |
| SCHEMBL34473259 | 0.73 | OPRM1 (0.46) | OPRM1SIGMAR1KCNH2CHRM2CHRM3 | |
| SCHEMBL25104898 | 0.72 | BCHE (0.49) | OPRM1SIGMAR1CHRM2CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604401-A | QUINOLINE-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |