Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylphosphonium SCHEMBL2000466 | 0.83 | TSHR (0.58) | TSHRDAONAPRTTP53SRD5A2 | |
| Hydrochloric Acid SCHEMBL11806139 | 0.78 | MAPT (0.57) | ALDH1A1CA12CA9SMN1; SMN2 | |
| Tetraphenylphosphonium SCHEMBL21957806 | 0.77 | CA2 (0.62) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL4961359 | 0.77 | TSHR (0.93) | TSHRDAONAPRTTP53SRD5A2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.77 | TSHR (0.92) | TSHRDAONAPRTTP53SRD5A2 | |
| Tetraphenylphosphonium SCHEMBL158514 | 0.77 | HIF1A (0.47) | TSHRALDH1A1CA1CA2CA12 | |
| Tetraphenylphosphonium SCHEMBL4388860 | 0.75 | CA2 (0.46) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL9250012 | 0.74 | TSHR (0.86) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzoic Acid SCHEMBL137419 | 0.74 | TSHR (1.00) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzoic Acid SCHEMBL975929 | 0.74 | TSHR (1.00) | TSHRDAONAPRTTP53SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585889-A | Carbonylation process for the production of monoesters aromatic dicarboxylic acids from phosphonium salts | EASTMAN KODAK COMPANY (US) | 1986-04-29 | — | — | US | disclosed |