Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901798 | 0.82 | ACHE (0.45) | S1PR1ACHEBCHESLC6A4 | |
| SCHEMBL10901658 | 0.81 | BCHE (0.60) | QDPRS1PR1ACHEBCHESLC6A2 | |
| SCHEMBL10898354 | 0.80 | S1PR1 (0.46) | QDPRS1PR1CHRNA7 | |
| SCHEMBL10901484 | 0.80 | S1PR1 (0.44) | S1PR1ACHEBCHESLC6A4 | |
| SCHEMBL10902488 | 0.80 | CHRM2 (0.53) | ACHEBCHECHRNA7CHRNB2CHRNA4 | |
| SCHEMBL11338695 | 0.80 | QDPR (0.50) | QDPRASAH1FAAHNAAACHRNA7 | |
| SCHEMBL10902916 | 0.79 | CHRM2 (0.52) | ACHEBCHECHRNA7CHRNB2CHRNA4 | |
| SCHEMBL2721292 | 0.79 | ACHE (0.52) | ACHEBCHECHRNA7SLC6A2SLC6A4 | |
| SCHEMBL29383343 | 0.79 | ACHE (0.52) | ACHEBCHECHRNA7SLC6A2SLC6A4 | |
| SCHEMBL10899844 | 0.79 | CHRM2 (0.52) | ACHEBCHECHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |