Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 8/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901798 | 0.83 | ACHE (0.45) | S1PR1ACHEBCHEDRD2SLC6A4 | |
| SCHEMBL11336429 | 0.82 | MAOB (0.43) | S1PR1BCHEMAOAMAOBDRD2 | |
| SCHEMBL10901412 | 0.80 | QDPR (0.46) | S1PR1ACHEBCHESLC6A4 | |
| SCHEMBL10903326 | 0.80 | ACHE (0.66) | ACHEBCHEMAOAMAOBSLC6A4 | |
| SCHEMBL10898354 | 0.77 | S1PR1 (0.46) | S1PR1 | |
| SCHEMBL10906163 | 0.77 | ACHE (0.42) | ACHEBCHEMAOAMAOB | |
| SCHEMBL10901490 | 0.76 | MAOB (0.40) | S1PR1ACHEMAOAMAOBDRD2 | |
| SCHEMBL10901658 | 0.75 | BCHE (0.60) | S1PR1ACHEBCHEMAOAMAOB | |
| SCHEMBL11334591 | 0.74 | CYP1A2 (0.43) | BCHEMAOAMAOBDRD2P2RY14 | |
| SCHEMBL11335029 | 0.71 | MAOB (0.45) | MAOAMAOBP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | claimed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |