Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26977331 | 0.92 | ATM (0.49) | HCAR2ATMEPHX1HRH1HTT | |
| SCHEMBL505930 | 0.92 | ATM (0.49) | HCAR2ATMEPHX1HRH1HTT | |
| SCHEMBL4165033 | 0.92 | ATM (0.49) | HCAR2ATMEPHX1HRH1HTT | |
| Cyclohexyl Fumarate SCHEMBL17073964 | 0.89 | NAAA (0.46) | HCAR2ATMEPHX1NAAAHRH1 | |
| Cyclohexyl Fumarate SCHEMBL17073973 | 0.89 | NAAA (0.46) | HCAR2ATMEPHX1NAAAHRH1 | |
| SCHEMBL528295 | 0.88 | ATM (0.49) | HCAR2ATMEPHX1NAAAHTT | |
| SCHEMBL609184 | 0.88 | ATM (0.49) | HCAR2ATMEPHX1NAAAHTT | |
| SCHEMBL528296 | 0.88 | ATM (0.49) | HCAR2ATMEPHX1NAAAHTT | |
| Cyclohexyl Fumarate SCHEMBL528630 | 0.86 | ATM (0.47) | HCAR2ATMEPHX1NAAAHTT | |
| SCHEMBL4156019 | 0.86 | ATM (0.47) | HCAR2ATMEPHX1NAAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567035-A | Low molecular weight hair spray | GAF CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |