Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17879526 | 0.87 | LMNA (0.46) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL17879527 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL25392464 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL16970698 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL25752840 | 0.81 | MAPT (0.40) | ALDH1A1HTTSMN1; SMN2POLBMAPT | |
| SCHEMBL12525555 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL15497032 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL14008890 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12492506 | 0.80 | MAPT (0.40) | ALDH1A1LMNAKMT2AMEN1HTT | |
| Hydrochloric Acid SCHEMBL29891870 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044184-A1 | PENTAFLUOROSULFUR IMINO HETEROCYCLIC COMPOUNDS AS BACE-1 INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |