Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424447 | 0.92 | KDM4E (0.59) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 | |
| SCHEMBL9485929 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9622132 | 0.86 | KDM4E (0.51) | KDM4EPTGS1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10388487 | 0.84 | KDM4E (0.56) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 | |
| SCHEMBL2453681 | 0.84 | KDM4E (0.56) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 | |
| SCHEMBL15961373 | 0.81 | ALDH1A1 (0.53) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 | |
| SCHEMBL1697068 | 0.80 | HSD11B1 (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL931068 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7456021 | 0.80 | KDM4E (0.58) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 | |
| SCHEMBL7815882 | 0.79 | KDM4E (0.50) | KDM4EAKR1C3AKR1C2PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590290-A | REACTING DIMETHYL SULFATE WITH G-HYDROXY-1-NAPHTHOIC ACID | AMERICAN CYANAMID COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4590290-A | REACTING DIMETHYL SULFATE WITH G-HYDROXY-1-NAPHTHOIC ACID | AMERICAN CYANAMID COMPANY (US) | 1986-05-20 | — | — | US | disclosed |