Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459894 | 0.91 | KDM4E (0.53) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL11718070 | 0.89 | KDM4E (0.53) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL15917514 | 0.87 | MTNR1A (0.50) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL3015936 | 0.84 | HSD17B1 (0.56) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL10902014 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL2453681 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL29276964 | 0.83 | CA12 (0.47) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL11507377 | 0.83 | POLB (0.56) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL15961373 | 0.81 | ALDH1A1 (0.53) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL11598223 | 0.81 | SLC2A1 (0.48) | KDM4EALDH1A1AKR1C3AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914243-A | Production of 2-alkoxy or aryl(lower)alkoxy-6-methoxy-1-naphthalenecarboxaldehyde | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |
| US-4866197-A | Production of N-((2-alkoxy-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)carbonyl)-N-methylglycine esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |