Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439799 | 0.87 | PTPRC (0.50) | GABRA1GABRB2AKR1B1ALDH1A1NPC1 | |
| SCHEMBL5824164 | 0.86 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1ALDH1A1NPC1 | |
| SCHEMBL6406262 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2AKR1B1ALDH1A1NPC1 | |
| SCHEMBL1646926 | 0.83 | ALDH1A1 (0.52) | GABRA1GABRB2AKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4626943 | 0.81 | AKR1B1 (0.41) | GABRA1GABRB2AKR1B1ALDH1A1NPC1 | |
| SCHEMBL2362466 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1ALDH1A1CYP3A4 | |
| SCHEMBL29900352 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1ALDH1A1CYP3A4 | |
| SCHEMBL27735945 | 0.78 | DPP4 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL31290769 | 0.77 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL1334151 | 0.77 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131191-B1 | ORGANOCLAY-ANTIOZONANT COMPLEX | GEORGIA KAOLIN COMPANY, INC. (US) | 1986-11-26 | — | — | EP | claimed |
| US-4532285-A | Mixing smectite clay with quaternary amine, polar solvent, antiozonant to form expanded organoclay derivative complexed with antiozonant | GEORGIA KAOLIN COMPANY, INC. (US) | 1985-07-30 | — | — | US | claimed |
| EP-0131191-A1 | Organoclay-antiozonant complex | GEORGIA KAOLIN COMPANY, INC. (US) | 1985-01-16 | — | — | EP | claimed |
| EP-0131191-B1 | ORGANOCLAY-ANTIOZONANT COMPLEX | GEORGIA KAOLIN COMPANY, INC. (US) | 1986-11-26 | — | — | EP | disclosed |