Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783292 | 0.88 | VCAM1 (0.55) | MAPK1POLBGAAALDH1A1TDP1 | |
| SCHEMBL10903202 | 0.85 | ALDH1A1 (0.56) | GAALMNAALDH1A1CES1CES2 | |
| SCHEMBL30435123 | 0.84 | MAPK1 (0.60) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL11301789 | 0.84 | MAPK1 (0.60) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL9760328 | 0.81 | MAPK1 (0.47) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL10902711 | 0.81 | ALDH1A1 (0.54) | LMNAALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL10903201 | 0.80 | MAPK1 (0.62) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL11329074 | 0.79 | MAPK1 (0.51) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL9836297 | 0.78 | C5AR1 (0.42) | POLBGAAALDH1A1CES1CES2 | |
| SCHEMBL11335012 | 0.78 | GAA (0.51) | MAPK1POLBSRD5A2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618714-A | NITRATION, REDUCTION, DECHLORINATION OF CHLORONITROBENZOPHENONES OBTAINED FROM A NITROBENZOYL CHLORIDE AND CHLOROBENZENE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1986-10-21 | — | — | US | claimed |
| US-4618714-A | NITRATION, REDUCTION, DECHLORINATION OF CHLORONITROBENZOPHENONES OBTAINED FROM A NITROBENZOYL CHLORIDE AND CHLOROBENZENE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1986-10-21 | — | — | US | disclosed |