Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712444 | 0.82 | NR4A1 (0.53) | MAPK1SRD5A2ALDH1A1L3MBTL1CES1 | |
| SCHEMBL10903045 | 0.81 | MAPK1 (0.50) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL1812262 | 0.81 | AKR1C3 (0.48) | MAPK1POLBGAALMNAALDH1A1 | |
| SCHEMBL10416822 | 0.80 | MAPK1 (0.43) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL9712528 | 0.80 | AKR1C3 (0.50) | MAPK1SRD5A2GAALMNAALDH1A1 | |
| SCHEMBL7651794 | 0.78 | CYP19A1 (0.45) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL10903201 | 0.76 | MAPK1 (0.62) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL11329074 | 0.75 | MAPK1 (0.51) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL11335012 | 0.74 | GAA (0.51) | MAPK1POLBSRD5A2GAALMNA | |
| SCHEMBL11141757 | 0.74 | SRD5A2 (0.51) | MAPK1POLBSRD5A2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075298-A | Antibiotics | ROUSSEL UCLAF (FR) | 1991-12-24 | — | — | US | disclosed |