Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903600 | 0.81 | SLC22A6 (0.33) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL10906199 | 0.76 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4SLC22A6 | |
| SCHEMBL10905759 | 0.75 | FFAR3 (0.38) | CHRNB2CHRNB4CHRNA4GABRPGABRD | |
| SCHEMBL103866 | 0.72 | — | — | |
| SCHEMBL105805 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL4578644 | 0.70 | CHRNB2 (0.40) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL10903595 | 0.70 | SLC7A5 (0.32) | — | |
| SCHEMBL22384141 | 0.69 | SLC22A6 (0.38) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL1144278 | 0.67 | SLC22A6 (0.36) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL29953499 | 0.67 | SLC22A6 (0.36) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |