Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906180 | 0.83 | GABRP (0.41) | CHRNB2CHRNA4CHRNB4BMP1 | |
| SCHEMBL10906182 | 0.78 | — | — | |
| SCHEMBL10903600 | 0.78 | SLC22A6 (0.33) | SLC22A6 | |
| SCHEMBL10903617 | 0.76 | CACNA2D1 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3SLC22A6 | |
| SCHEMBL10905468 | 0.75 | MTOR (0.51) | — | |
| SCHEMBL10905414 | 0.72 | — | — | |
| SCHEMBL10905759 | 0.72 | FFAR3 (0.38) | CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL103866 | 0.69 | — | — | |
| SCHEMBL105805 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL4578644 | 0.68 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |