Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903617 | 0.81 | CACNA2D1 (0.35) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL10906588 | 0.79 | GABRP (0.43) | PHF8KDM2A | |
| SCHEMBL10906199 | 0.78 | CHRNB2 (0.33) | SLC22A6 | |
| SCHEMBL1144278 | 0.77 | SLC22A6 (0.36) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL10905759 | 0.76 | FFAR3 (0.38) | ALDH1A1PHF8KDM2AMAPT | |
| SCHEMBL103866 | 0.74 | — | — | |
| SCHEMBL105805 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4578644 | 0.72 | CHRNB2 (0.40) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL22384141 | 0.70 | SLC22A6 (0.38) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL29953499 | 0.68 | SLC22A6 (0.36) | SLC22A6CACNA2D1CACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |