Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616402 | 0.88 | ESR1 (0.43) | ESR1OPRD1PLAAALPGKDR | |
| SCHEMBL10782342 | 0.71 | ESR1 (0.50) | ESR1PLAAALPGKDRHDAC4 | |
| SCHEMBL9249012 | 0.70 | KMT2A (0.39) | OPRD1PLAAALPGSMN1; SMN2ACHE | |
| Imidazole SCHEMBL27498908 | 0.70 | DHODH (0.44) | HTTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL786798 | 0.69 | ESR1 (0.50) | ESR1OPRD1PLAAALPGSMN1; SMN2 | |
| SCHEMBL8013500 | 0.69 | ESR1 (0.44) | ESR1PLAAALPGSMN1; SMN2TSHR | |
| SCHEMBL11078694 | 0.67 | ESR1 (0.54) | ESR1PLAAALPGKDRSMN1; SMN2 | |
| SCHEMBL28848047 | 0.67 | ESR1 (0.54) | ESR1PLAAALPGKDRSMN1; SMN2 | |
| Imidazole SCHEMBL15823518 | 0.67 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| Imidazole SCHEMBL15824068 | 0.67 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628105-A | BENZOYL SUBSTITUTED IMIDAZOLES | CIBA-GEIGY CORPORATION (US) | 1986-12-09 | — | — | US | disclosed |
| US-4587311-A | Novel imidazolides and their use as curing agents for polyepoxide compounds | CIBA-GEIGY CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |