SCHEMBL616402

SCHEMBL616402

Cc1cc(C)c(C(=O)n2ccnc2-c2ccccc2)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
OPRD1 P41143 1/20 0.43
PLAA Q9Y263 1/20 0.42
ALPG P10696 1/20 0.41
KDR P35968 6/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
FLT1 P17948 3/20 0.38
FLT4 P35916 3/20 0.38
HTT P42858 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL10904641 0.88 ESR1 (0.38) ESR1OPRD1PLAAALPGKDR
SCHEMBL10782342 0.81 ESR1 (0.50) ESR1PLAAALPGKDRCA12
SCHEMBL9249012 0.80 KMT2A (0.39) OPRD1PLAAALPGSMN1; SMN2HTT
SCHEMBL786798 0.79 ESR1 (0.50) ESR1OPRD1PLAAALPGTSHR
SCHEMBL8013500 0.78 ESR1 (0.44) ESR1PLAAALPGTSHRSMN1; SMN2
SCHEMBL11078694 0.76 ESR1 (0.54) ESR1PLAAALPGKDRMAPT
SCHEMBL28848047 0.76 ESR1 (0.54) ESR1PLAAALPGKDRMAPT
SCHEMBL9250290 0.74 ALDH1A1 (0.42) OPRD1PLAAALPGMAPTTSHR
SCHEMBL10668273 0.73 ESR1 (0.51) ESR1PLAAALPGKDRCA12
SCHEMBL28035198 0.73 ESR1 (0.51) ESR1PLAAALPGMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0124482-B1 IMIDAZOLIDES AND THEIR USE AS CURING AGENTS FOR POLYEPOXIDES CIBA-GEIGY AG (CH) 1989-11-08 EP claimed
US-4628105-A BENZOYL SUBSTITUTED IMIDAZOLES CIBA-GEIGY CORPORATION (US) 1986-12-09 US claimed
US-4587311-A Novel imidazolides and their use as curing agents for polyepoxide compounds CIBA-GEIGY CORPORATION (US) 1986-05-06 US claimed
EP-0124482-A2 Imidazolides and their use as curing agents for polyepoxides CIBA-GEIGY AG (CH) 1984-11-07 EP claimed
CN-115380023-B Polyhydroxy resin, epoxy resin, method for producing same, epoxy resin composition using same, and cured product 日铁化学材料株式会社 2025-04-11 CN disclosed
CN-119161272-A Polyhydroxy resin, epoxy resin, method for producing same, epoxy resin composition using same, and cured product 日铁化学材料株式会社 2024-12-20 CN disclosed
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
CN-115195104-B Dual precursor resin system for additive manufacturing with dual cure resins 卡本有限公司 2023-12-05 CN disclosed
US-11814472-B2 Epoxy dual cure resins for additive manufacturing CARBON, INC. (US) 2023-11-14 US disclosed
US-20230143277-A1 DUAL CURE STEREOLITHOGRAPHY RESINS CONTAINING DIELS-ALDER ADDUCTS CARBON INC (US) 2023-05-11 US disclosed
US-11629202-B2 Dual cure stereolithography resins containing thermoplastic particles CARBON, INC. (US) 2023-04-18 US disclosed
US-4628105-A BENZOYL SUBSTITUTED IMIDAZOLES CIBA-GEIGY CORPORATION (US) 1986-12-09 US disclosed
EP-0194232-A2 Curable composition containing an epoxy resin, an imidazolide and a polysulfonic resin CIBA-GEIGY AG (CH) 1986-09-10 EP disclosed
EP-0190998-A1 Copolymerizable dibenzalacetone-palladium complexes and their use CIBA-GEIGY AG (CH) 1986-08-13 EP disclosed
US-4587311-A Novel imidazolides and their use as curing agents for polyepoxide compounds CIBA-GEIGY CORPORATION (US) 1986-05-06 US disclosed
EP-0176484-A2 Durable mixtures containing diethylphenyl-biguanide, and their use CIBA-GEIGY AG (CH) 1986-04-02 EP disclosed
US-4579916-A IMPROVED STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed
EP-0146498-A2 Hardenable composition containing an epoxy resin, an imide and a hardening catalyst CIBA-GEIGY AG (CH) 1985-06-26 EP disclosed
EP-0124482-A2 Imidazolides and their use as curing agents for polyepoxides CIBA-GEIGY AG (CH) 1984-11-07 EP disclosed