Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL11180188 | 0.87 | LMNA (0.67) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL3095350 | 0.87 | LMNA (0.67) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL6071932 | 0.87 | LMNA (0.67) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL8580726 | 0.87 | CA2 (0.67) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL4313661 | 0.87 | CA2 (0.67) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL9067666 | 0.85 | FFAR3 (0.59) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL8616475 | 0.85 | FFAR3 (0.59) | CA2CA12CA1CA9CA14 | |
| Paraben SCHEMBL1685437 | 0.84 | CA2 (0.80) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL8482471 | 0.83 | CA2 (0.61) | CA2CA12CA1CA9CA14 | |
| Hydroquinone SCHEMBL19056220 | 0.83 | CA2 (0.61) | CA2CA12CA1CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119533-B1 | POLYCARBONATE RESIN MIXTURE | GENERAL ELECTRIC COMPANY (US) | 1986-12-03 | — | — | EP | claimed |