Hydroquinone

Hydroquinone

SCHEMBL8580726

O=C(O)O.Oc1ccc(O)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.67
CA1 P00915 5/20 0.67
CA12 O43570 4/20 0.67
CA3 P07451 4/20 0.67
CA4 P22748 4/20 0.67
CA9 Q16790 4/20 0.67
CA14 Q9ULX7 4/20 0.67
MAPT P10636 4/20 0.67
TYR P14679 3/20 0.67
CA5A P35218 3/20 0.67
CA5B Q9Y2D0 3/20 0.67
LMNA P02545 3/20 0.67
KMT2A Q03164 3/20 0.67
HPGD P15428 2/20 0.67
MEN1 O00255 2/20 0.67
ALDH1A1 P00352 2/20 0.67
RAB9A P51151 2/20 0.67
KDM4E B2RXH2 1/20 0.67
NPC1 O15118 1/20 0.67
GMNN O75496 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL4313661 1.00 CA2 (0.67) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL19056220 0.96 CA2 (0.61) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL8482471 0.96 CA2 (0.61) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL28408333 0.88 CPT1B (0.63) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL5051994 0.87 CA3 (0.89) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL5051991 0.87 CA3 (0.89) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL10904652 0.87 CA2 (0.52) CA2CA1CA12CA3CA4
Phenol SCHEMBL252449 0.85 CA12 (0.79) CA2CA1CA12CA3CA4
Hydroquinone SCHEMBL2505159 0.85 CA2 (0.58) CA2CA1CA12CA3CA4
Phenol SCHEMBL7570924 0.85 CA12 (0.79) CA2CA1CA12CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162459-A Cyclic Hydroquinone Polycarbonate GENERAL ELECTRIC COMPANY (US) 1992-11-10 US claimed
US-5162458-A Blending amorphous and oligomer polycarbonates and a catalyst, nonflamable; shaped articles GENERAL ELECTRIC COMPANY (US) 1992-11-10 US claimed
US-5153276-A Solvent resistant polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1992-10-06 US claimed
JP-2215831-A None JP disclosed
CN-119242013-A Flame retardant material, preparation method thereof and product 江苏博云塑业股份有限公司 2025-01-03 CN disclosed
CN-119081387-A Flame retardant material, preparation method and product thereof 江苏博云塑业股份有限公司 2024-12-06 CN disclosed
EP-0849305-A2 Method for preparing polycarbonate by solid state polymerization GENERAL ELECTRIC COMPANY (US) 1998-06-24 EP disclosed
US-5717056-A Method for preparing polycarbonate by solid state polymerization GENERAL ELECTRIC COMPANY (US) 1998-02-10 US disclosed
US-5693722-A TRANSESTERIFICATION IN A MELT OF A POLYESTER/CARBONATE AND A CYCLIC POLYCARBONATE BAYER CORPORATION (US) 1997-12-02 US disclosed
US-5637655-A CYCLIC CARBONATE IS TRANSESTERIFIED WITH POLYMER RESIN BAYER CORPORATION (US) 1997-06-10 US disclosed
US-5605979-A MELT TRANSESTERIFICATION OF POLYESTERS OR POLYCARBONATES WITH CYCLIC CARBONATES BAYER CORPORATION (US) 1997-02-25 US disclosed
US-5153276-A Solvent resistant polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1992-10-06 US disclosed
US-5153276-A Solvent resistant polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1992-10-06 US disclosed
US-4994547-A Solvent resistant GENERAL ELECTRIC COMPANY (US) 1991-02-19 US disclosed
US-4973729-A PHOSGENE, TURBULENT MIXING GENERAL ELECTRIC COMPANY (US) 1990-11-27 US disclosed
JP-H02215831-A LINEAR COPOLYCARBONATE FROM HYDROQUINONE/BISPHENOL CYCLIC COPOLYCARBONATE GENERAL ELECTRIC CO <GE> 1990-08-28 JP disclosed
EP-0378857-A2 Method for preparing hydroquinone and hydroquinone-bisphenol A bischloroformates GENERAL ELECTRIC COMPANY (US) 1990-07-25 EP disclosed
EP-0375935-A2 Hydroquine-bisphenol cyclic copolycarbonates and method of preparation GENERAL ELECTRIC COMPANY (US) 1990-07-04 EP disclosed
EP-0375936-A2 Linear copolycarbonates from hydroquinone-bisphenol cyclic copolycarbonates GENERAL ELECTRIC COMPANY (US) 1990-07-04 EP disclosed
US-4920200-A CONVERSION TO SOLVENT-RESISTANT, LINEAR AND SOMETIMES CRYSTALLINE POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1990-04-24 US disclosed