Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904335 | 0.85 | FDPS (0.46) | MAPTHPGDFDPSCA2FFAR1 | |
| SCHEMBL3858633 | 0.83 | CA2 (0.37) | MAPTFDPSACHEBACE1CA2 | |
| SCHEMBL9331686 | 0.83 | GPR84 (0.44) | MAPTFDPSFFAR1FFAR4 | |
| SCHEMBL15412278 | 0.83 | GPR84 (0.44) | MAPTFDPSFFAR1FFAR4 | |
| SCHEMBL27998671 | 0.79 | FFAR4 (0.50) | TSHRALDH1A1MAPTFFAR1FFAR4 | |
| SCHEMBL27872756 | 0.79 | CA2 (0.42) | MAPTFDPSCA2MAPK1FFAR1 | |
| SCHEMBL141909 | 0.79 | GPR84 (0.39) | MAPTFDPSCA2MAPK1FFAR1 | |
| SCHEMBL9136864 | 0.78 | FDPS (0.49) | MAPTFDPSCA2FFAR1FFAR4 | |
| SCHEMBL9771300 | 0.78 | FDPS (0.49) | MAPTFDPSCA2FFAR1FFAR4 | |
| SCHEMBL6447112 | 0.78 | FDPS (0.49) | MAPTFDPSCA2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598103-A | 1,8-DIAZABICYCLO-5.4.0)ON DEC-7-ENE OR A SALT THEREOF; ORGANIC TIN COMPOUND; ORGANIC LEAD COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |