Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342617 | 0.82 | MTOR (0.58) | MTORNPY5RMEN1KMT2AALDH1A1 | |
| SCHEMBL10906199 | 0.75 | CHRNB2 (0.33) | — | |
| SCHEMBL10931873 | 0.72 | POLB (0.63) | LMNAHPGDALDH1A1TSHRKDM4E | |
| SCHEMBL11754900 | 0.72 | MTOR (0.72) | MTORNPY5RMEN1KMT2AATM | |
| SCHEMBL10906601 | 0.71 | GAA (0.49) | MTORLMNAHPGDKDM4EHDAC3 | |
| Fenuron SCHEMBL8366971 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ATSHR | |
| Fenuron SCHEMBL62004 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ATSHR | |
| Fenuron SCHEMBL10806698 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ATSHR | |
| Fenuron SCHEMBL9451054 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ATSHR | |
| SCHEMBL11270620 | 0.70 | MTOR (0.59) | MTORNPY5RMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |