Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905765 | 0.78 | HDAC8 (0.46) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10906611 | 0.76 | KMT2A (0.44) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10903597 | 0.74 | GAA (0.35) | GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10906136 | 0.72 | LTA4H (0.45) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10905761 | 0.72 | MAPT (0.41) | MTORHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10905468 | 0.71 | MTOR (0.51) | MTORHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10906603 | 0.71 | LTA4H (0.46) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27477626 | 0.70 | MME (0.58) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10906180 | 0.70 | GABRP (0.41) | — | |
| SCHEMBL10906588 | 0.69 | GABRP (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |