Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908122 | 0.89 | GAA (0.47) | GAAALDH1A1LMNAPPIDKDM4E | |
| SCHEMBL10908314 | 0.87 | HPGD (0.56) | GAAALDH1A1LMNAPPIDTACR1 | |
| SCHEMBL10908208 | 0.84 | ALDH1A1 (0.51) | GAAALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL10909336 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNATP53TACR1HPGD | |
| SCHEMBL3835577 | 0.75 | MEN1 (0.55) | LMNAPPIDKDM4EMAPTMEN1 | |
| SCHEMBL10898232 | 0.75 | MEN1 (0.72) | GAAALDH1A1TP53KDM4EMAPT | |
| SCHEMBL10950927 | 0.74 | TSHR (0.58) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL3519792 | 0.74 | LMNA (0.50) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL655874 | 0.74 | POLB (0.58) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13572974 | 0.73 | FFAR1 (0.48) | GAAALDH1A1LMNACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603145-A | Antiatherosclerotic diphenyl alkanamides | AMERICAN CYANAMID COMPANY (US) | 1986-07-29 | — | — | US | disclosed |