SCHEMBL10909336

SCHEMBL10909336

CCCCNC(=O)CC(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
THRB P10828 1/20 0.49
HPGD P15428 3/20 0.49
TP53 P04637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TACR1 P25103 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SLC6A3 Q01959 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440486 0.76 EPHX1 (0.49) ALDH1A1LMNATHRBTP53NPSR1
SCHEMBL10905935 0.75 GAA (0.51) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL29306716 0.74 HPGD (0.66) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL10909306 0.74 TACR1 (0.71) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL11344157 0.74 HDAC3 (0.48) ALDH1A1LMNAMEN1KMT2ATHRB
SCHEMBL11344160 0.74 HDAC3 (0.48) ALDH1A1LMNAMEN1KMT2ATHRB
SCHEMBL23903436 0.73 HTT (0.72) ALDH1A1MEN1KMT2AHPGDSMN1; SMN2
SCHEMBL10909880 0.73 L3MBTL1 (0.47) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL6359381 0.72 HDAC3 (0.71) MEN1KMT2AHPGDHDAC3HDAC1
SCHEMBL3995030 0.71 TRPV1 (0.65) ALDH1A1LMNAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4603145-A Antiatherosclerotic diphenyl alkanamides AMERICAN CYANAMID COMPANY (US) 1986-07-29 US disclosed