Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090404 | 0.84 | P2RX3 (0.38) | TKTTAAR1P2RX3P2RX2HRH3 | |
| SCHEMBL1090837 | 0.80 | DHFR (0.44) | — | |
| SCHEMBL19461895 | 0.79 | TLR8 (0.43) | — | |
| SCHEMBL2114974 | 0.79 | RAB9A (0.47) | — | |
| SCHEMBL2115272 | 0.78 | TNK2 (0.42) | TAAR1 | |
| SCHEMBL1090705 | 0.78 | HDAC1 (0.39) | HRH3 | |
| SCHEMBL2113390 | 0.78 | NPC1 (0.52) | TAAR1LMNA | |
| SCHEMBL4891191 | 0.78 | DHFR (0.45) | TKTP2RX3P2RX2 | |
| SCHEMBL1090496 | 0.77 | GRM5 (0.43) | P2RX3P2RX2 | |
| SCHEMBL2114996 | 0.77 | HTT (0.49) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153625-B2 | Nitrogen-containing heterocyclic compounds and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |