Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907495 | 0.76 | KMT2A (0.46) | LTA4HALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL1033607 | 0.75 | TP53 (0.44) | LTA4HALDH1A1GLATSHRTP53 | |
| SCHEMBL3992095 | 0.73 | TP53 (0.42) | NPSR1LTA4HALDH1A1GLATSHR | |
| SCHEMBL7262850 | 0.73 | NPSR1 (0.54) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL10348556 | 0.72 | NPSR1 (0.64) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL11589373 | 0.71 | TP53 (0.43) | NPSR1LTA4HALDH1A1GLATSHR | |
| SCHEMBL10905444 | 0.71 | KMT2A (0.46) | ALDH1A1TSHRTP53KMT2AHTT | |
| SCHEMBL28480691 | 0.70 | RAB9A (0.50) | LTA4HALDH1A1GLATSHRTP53 | |
| SCHEMBL3868884 | 0.69 | MEN1 (0.47) | ALDH1A1GLATSHRTP53KMT2A | |
| SCHEMBL10906150 | 0.68 | LTA4H (0.30) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |