Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903602 | 0.80 | HDAC3 (0.47) | KMT2AADRA2CALDH1A1HPGDHSD11B1 | |
| SCHEMBL10906612 | 0.79 | HDAC6 (0.50) | KMT2AL3MBTL1MAPTTDP1HDAC1 | |
| SCHEMBL10906149 | 0.76 | NPSR1 (0.39) | KMT2ALTA4HALDH1A1POLBCYP3A4 | |
| SCHEMBL10906184 | 0.75 | MLYCD (0.48) | KMT2AALDH1A1HPGDL3MBTL1POLB | |
| SCHEMBL1232674 | 0.75 | HDAC6 (0.55) | HDAC1HDAC6 | |
| SCHEMBL28827956 | 0.75 | ADRA2C (0.66) | KMT2AADRA2CALDH1A1HPGDPOLB | |
| SCHEMBL10905444 | 0.74 | KMT2A (0.46) | KMT2AALDH1A1L3MBTL1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL11480006 | 0.74 | FFAR1 (0.51) | — | |
| SCHEMBL2447478 | 0.73 | HDAC6 (0.62) | HDAC1HDAC6 | |
| SCHEMBL28215034 | 0.73 | HDAC6 (0.62) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |